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human ICMT shRNA silencing Adenovirus

Name 
Ad-h-ICMT-shRNA
Cat No 
shADV-211756
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ICMT.

shADV-211756
Ad-h-ICMT-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ICMT (isoprenylcysteine carboxyl methyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HSTE14; MST098; MSTP098; PCCMT; PCMT; PPMT
Description (Vector)
ICMT encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
Gene ID
23463
Gene Name (Vector)
isoprenylcysteine carboxyl methyltransferase
Gene Symbol
ICMT
HGNC ID
HGNC:5350
ORF Size (aa)
855
ORF Size (bp)
855 bp
RefSeq ID
NM_012405
RefSeq Synonyms
NM_012405, BC028168,
Species
human
UniGene ID
Hs.515688

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.