human HTRA2 Over-expression AAV

Name 
AAV-h-HTRA2
Cat No 
AAV-211714
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HTRA2.

AAV-211714
AAV-h-HTRA2

Ready-to-use AAV expressing Human HTRA2 (HtrA serine peptidase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
OMI; PARK13; PRSS25;
Description (Vector)
HTRA2 encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
Gene ID
27429
Gene Name (Vector)
HtrA serine peptidase 2
Gene Symbol
HTRA2
HGNC ID
HGNC:14348
ORF Size (aa)
1377
ORF Size (bp)
1377 bp
RefSeq ID
NM_013247
RefSeq Synonyms
NM_145074, NM_013247, NM_001321728, NM_001321727, BC000096,
Species
human
UniGene ID
Hs.716372

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.