mouse HTRA2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Htra2.
shADV-261790
Ad-m-HTRA2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Htra2 (HtrA serine peptidase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI481710; mnd2; Omi; Prss25
Description (Vector)
Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
Gene ID
64704
Gene Name (Vector)
HtrA serine peptidase 2
Gene Symbol
Htra2
ORF Size (aa)
1377
ORF Size (bp)
1377 bp
RefSeq ID
NM_019752
RefSeq Synonyms
NM_019752, BC049880,
Species
mouse
UniGene ID
Mm.21880
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.