human HP1BP3 Over-expression AAV

Name 
AAV-h-HP1BP3
Cat No 
AAV-211491
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HP1BP3.

AAV-211491
AAV-h-HP1BP3

Ready-to-use AAV expressing Human HP1BP3 (heterochromatin protein 1 binding protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
heterochromatin protein 1-binding protein 3; HP1BP74; HP1-BP74; Protein HP1-BP74
Description (eCommerce)
HP1BP3 is a component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity. Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self-renewal. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5SSJ5].
Gene ID
50809
Gene Name (eCommerce)
heterochromatin protein 1 binding protein 3
Gene Name (Vector)
heterochromatin protein 1 binding protein 3
Gene Symbol
HP1BP3
HGNC ID
HGNC:24973
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1206
ORF Size (bp)
1206 bp
Protein Name (eCommerce)
Heterochromatin protein 1-binding protein 3
RefSeq ID
NM_016287
RefSeq Synonyms
NM_016287, BC046170, BC045660, BC032139,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
HP1BP3 is a component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity. Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self-renewal. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5SSJ5].
UniGene ID
Hs.142442
UniProt ID (eCommerce)
Q5SSJ5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.