human HOXB5 Over-expression AAV

Name 
AAV-h-HOXB5
Cat No 
AAV-211457
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HOXB5.

AAV-211457
AAV-h-HOXB5

Ready-to-use AAV expressing Human HOXB5 (homeobox B5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HHO.C10; HOX2; Hox2.1; HOX2A; HU-1
Description (Vector)
HOXB5 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
Gene ID
3215
Gene Name (Vector)
homeobox B5
Gene Symbol
HOXB5
HGNC ID
HGNC:5116
ORF Size (aa)
810
ORF Size (bp)
810 bp
RefSeq ID
NM_002147
RefSeq Synonyms
NM_002147, BC117247,
Species
human
UniGene ID
Hs.654456

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.