human HMGA1 Over-expression AAV

Name 
AAV-h-HMGA1
Cat No 
AAV-211259
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HMGA1.

AAV-211259
AAV-h-HMGA1

Ready-to-use AAV expressing Human HMGA1 (high mobility group AT-hook 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HMG-R; HMGA1A; HMGIY
Description (Vector)
HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
Gene ID
3159
Gene Name (Vector)
high mobility group AT-hook 1
Gene Symbol
HMGA1
HGNC ID
HGNC:5010
ORF Size (aa)
291
RefSeq ID
NM_002131
RefSeq Synonyms
NM_145905, NM_145903, NM_145902, NM_145901, NM_145899, NM_002131, NM_001319082, NM_001319081, NM_001319080, NM_001319079, NM_001319078, NM_001319077, BC071864, BC071863, BC067083, BC063434, BC015789, BC008832, BC004924,
Species
human
UniGene ID
Hs.703764

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.