human HEXIM2 Over-expression AAV

Name 
AAV-h-HEXIM2
Cat No 
AAV-210984
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HEXIM2.

AAV-210984
AAV-h-HEXIM2

Ready-to-use AAV expressing Human HEXIM2 (hexamethylene bisacetamide inducible 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hexamethylene bis-acetamide inducible 2; hexamethylene bis-acetamide-inducible protein 2; hexamethylene-bis-acetamide-inducible transcript 2; L3; MAQ1 paralog; protein HEXIM2
Description (eCommerce)
HEXIM2 (Hexamethylene bis-acetamide-inducible protein 2) is a transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA, HEXIM2 sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96MH2].
Gene ID
124790
Gene Name (eCommerce)
hexamethylene bisacetamide inducible 2
Gene Name (Vector)
hexamethylene bisacetamide inducible 2
Gene Symbol
HEXIM2
HGNC ID
HGNC:28591
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
861
ORF Size (bp)
861 bp
Protein Name (eCommerce)
Protein HEXIM2
RefSeq ID
NM_144608
RefSeq Synonyms
NM_144608, NM_001303444, NM_001303443, NM_001303442, NM_001303441, NM_001303440, NM_001303439, NM_001303438, NM_001303437, NM_001303436, BC025970, BC012474, BC003531,
Research Areas
RNA Binding,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
HEXIM2 (Hexamethylene bis-acetamide-inducible protein 2) is a transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA, HEXIM2 sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96MH2].
UniGene ID
Hs.56382
UniProt ID (eCommerce)
Q96MH2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.