human HEPN1 Over-expression AAV

Name 
AAV-h-HEPN1
Cat No 
AAV-210950
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HEPN1.

AAV-210950
AAV-h-HEPN1

Ready-to-use AAV expressing Human HEPN1 (hepatocellular carcinoma, down-regulated 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
HEPN1 is expressed in the liver, and encodes a short peptide that is localized predominantly to the cytoplasm. Transient transfection studies showed that expression of this gene significantly inhibited cell growth, and it may have a role in apoptosis. Expression of this gene is downregulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes (PMID:12971969). Also to note is that this gene maps to the 3'-noncoding region of HEPACAM gene (GeneID:220296) on the antisense strand (PMID:15885354).
Gene ID
641654
Gene Name (Vector)
hepatocellular carcinoma, down-regulated 1
Gene Symbol
HEPN1
HGNC ID
HGNC:34400
ORF Size (aa)
267
RefSeq ID
NM_001037558
RefSeq Synonyms
NM_001037558, BC156583, BC148521,
Species
human
UniGene ID
Hs.159863

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.