human HECTD3 Over-expression AAV

Name 
AAV-h-HECTD3
Cat No 
AAV-210928
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HECTD3.

AAV-210928
AAV-h-HECTD3

Ready-to-use AAV expressing Human HECTD3 (HECT domain E3 ubiquitin protein ligase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
E3 ubiquitin-protein ligase HECTD3; HECT domain containing E3 ubiquitin protein ligase 3; HECT domain-containing protein 3; HECT-type E3 ubiquitin transferase HECTD3
Description (eCommerce)
E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. HECTD3 mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP It also,mediatesubiquitination of STX8 (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5T447].
Gene ID
79654
Gene Name (eCommerce)
HECT domain E3 ubiquitin protein ligase 3
Gene Name (Vector)
HECT domain E3 ubiquitin protein ligase 3
Gene Symbol
HECTD3
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1734
ORF Size (bp)
1734 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase HECTD3
RefSeq ID
NM_024602
RefSeq Synonyms
NM_024602, BC130470, BC126352, BC019105,
Research Areas
Antigen Processing and Presentation,Immunology
Research Areas (Faceted)
immunology
Species
human
Target Sentence
E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. HECTD3 mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP It also,mediatesubiquitination of STX8 (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5T447].
UniGene ID
Hs.525084
UniProt ID (eCommerce)
Q5T447

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.