human HDAC8 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-210894
Availability:
3-5 weeks
Name:
AAV-h-HDAC8
This is an AAV expressing Human HDAC8.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HDAC8
- Gene Name
- histone deacetylase 8
- Gene ID
- 55869
- Gene Synonyms
- CDA07; CDLS5; HD8; HDACL1; MRXS6; RPD3; WTS
- ORF Size
- 1134 bp
- RefSeq#
- BC050433
- Gene Description
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.310536
- HGNC ID
- HGNC:13315
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