human GTF2A1 Over-expression AAV

Name 
AAV-h-GTF2A1
Cat No 
AAV-210628
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GTF2A1.

AAV-210628
AAV-h-GTF2A1

Ready-to-use AAV expressing Human GTF2A1 (general transcription factor IIA subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
general transcription factor IIA 1; General transcription factor IIA subunit 1; general transcription factor IIA, 1, 19/37kDa; glucose regulated protein, 58kD pseudogene; TF2A1; TFIIA; TFIIA alpha, p55; TFIIA alpha/beta subunits; TFIIA-42; TFIIAL; transcription initiation factor IIA subunit 1; transcription initiation factor TFIIA 42 kDa subunit
Description (eCommerce)
GTF2A1/TFIIA (general transcription factor IIA subunit 1) is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. gTF2A1/TFIIA in a complex with TBP mediates transcriptional activity [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/P52655].
Description (Vector)
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 (PubMed 8224848)). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.(supplied by OMIM, Jul 2010)
Gene ID
2957
Gene Name (eCommerce)
general transcription factor IIA subunit 1
Gene Name (Vector)
general transcription factor IIA subunit 1
Gene Symbol
GTF2A1
HGNC ID
HGNC:4646
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1131
ORF Size (bp)
1131 bp
Protein Name (eCommerce)
Transcription initiation factor IIA subunit 1
RefSeq ID
NM_015859
RefSeq Synonyms
NM_201595, NM_015859, NM_001278940, BC107156, BC107155,
Research Areas
Cancer,Chromatin Remodeling,Gene Expression,Host-Virus Interactions,Transcription Factor/Regulator,Viral Carcinogenesis
Research Areas (Faceted)
cancer,cell_biology,genetics,transcription_translation,infectious_disease
Species
human
Target Sentence
GTF2A1/TFIIA (general transcription factor IIA subunit 1) is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. gTF2A1/TFIIA in a complex with TBP mediates transcriptional activity [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/P52655].
UniGene ID
Hs.593630
UniProt ID (eCommerce)
P52655

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.