human GRWD1 Over-expression AAV

Name 
AAV-h-GRWD1
Cat No 
AAV-210569
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GRWD1.

AAV-210569
AAV-h-GRWD1

Ready-to-use AAV expressing Human GRWD1 (glutamate rich WD repeat containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CDW4; CUL4- and DDB1-associated WDR protein 4; glutamate rich WD repeat protein GRWD; glutamate-rich WD repeat-containing protein 1; GRWD; regulator of ribosome biogenesis 1 homolog; RRB1; WD repeat domain 28; WDR28
Description (eCommerce)
GRWD1/WDR28 contains five WD repeats and is a member of the WD family of proteins. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WD proteins are involved in a variety of cellular processes. GRWD1/WDR28 is proposed to play a role in ribosome biogenesis.
Description (Vector)
GRWD1 encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase.
Gene ID
83743
Gene Name (eCommerce)
glutamate rich WD repeat containing 1
Gene Name (Vector)
glutamate rich WD repeat containing 1
Gene Symbol
GRWD1
HGNC ID
HGNC:21270
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1341
ORF Size (bp)
1341 bp
Protein Name (eCommerce)
Glutamate-rich WD repeat-containing protein 1
RefSeq ID
NM_031485
RefSeq Synonyms
NM_031485, BC002440,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
GRWD1/WDR28 contains five WD repeats and is a member of the WD family of proteins. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WD proteins are involved in a variety of cellular processes. GRWD1/WDR28 is proposed to play a role in ribosome biogenesis.
UniGene ID
Hs.400625
UniProt ID (eCommerce)
Q9BQ67

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.