human GRK1 Over-expression AAV

Name
AAV-h-GRK1

Cat No
AAV-210537

Availability
4-5 weeks

This is an AAV expressing Human GRK1.

AAV-210537

AAV-h-GRK1

Ready-to-use AAV expressing Human GRK1 (G protein-coupled receptor kinase 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GPRK1; RHOK; RK

Description (Vector)

GRK1 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).

Gene ID

6011

Gene Name (Vector)

G protein-coupled receptor kinase 1

Gene Symbol

GRK1

HGNC ID

HGNC:10013

ORF Size (aa)

1692

ORF Size (bp)

1692 bp

RefSeq ID

NM_002929

RefSeq Synonyms

NM_002929, BC140945,

Species

human

UniGene ID

Hs.103501

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.