human GPX5 Over-expression AAV

Name 
AAV-h-GPX5
Cat No 
AAV-210469
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GPX5.

AAV-210469
AAV-h-GPX5

Ready-to-use AAV expressing Human GPX5 (glutathione peroxidase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HEL-S-75p
Description (Vector)
GPX5 belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike mRNAs for other characterized glutathione peroxidases, this mRNA does not contain a selenocysteine (UGA) codon. Thus, the encoded protein is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
2880
Gene Name (Vector)
glutathione peroxidase 5
Gene Symbol
GPX5
HGNC ID
HGNC:4557
ORF Size (aa)
663
ORF Size (bp)
663 bp
RefSeq ID
NM_001509
RefSeq Synonyms
NM_003996, NM_001509, BC111375,
Species
human
UniGene ID
Hs.248129

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.