human GPR56 Over-expression AAV

Name 
AAV-h-GPR56
Cat No 
AAV-210371
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ADGRG1.

AAV-210371
AAV-h-GPR56

Ready-to-use AAV expressing Human ADGRG1 (adhesion G protein-coupled receptor G1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BFPP; BPPR; GPR56; TM7LN4; TM7XN1
Description (Vector)
GPR56 encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
9289
Gene Name (Vector)
adhesion G protein-coupled receptor G1
Gene Symbol
ADGRG1
HGNC ID
HGNC:4512
ORF Size (aa)
2082
ORF Size (bp)
2082 bp
RefSeq ID
NM_005682
RefSeq Synonyms
NM_201525, NM_201524, NM_005682, NM_001290144, NM_001290143, NM_001290142, NM_001145774, NM_001145773, NM_001145772, NM_001145771, NM_001145770, BC008770,
Species
human
UniGene ID
Hs.513633

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.