human GPN1 Over-expression AAV

Name 
AAV-h-GPN1
Cat No 
AAV-210243
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GPN1.

AAV-210243
AAV-h-GPN1

Ready-to-use AAV expressing Human GPN1 (GPN-loop GTPase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ATP(GTP)-binding protein; ATPBD1A; GPN-loop GTPase 1; MBD2-interacting protein; MBDIN; NTPBP; RNA polymerase II associated protein 4; RNAPII-associated protein 4; RPAP4; XAB1; XPA binding protein 1, GTPase; XPA-binding protein 1
Description (eCommerce)
GPN-loop GTPase 1 (GPN1) forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. GPN1 may be involved in nuclear localization of XPA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9HCN4].
Description (Vector)
GPN1 encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described.
Gene ID
11321
Gene Name (eCommerce)
GPN-loop GTPase 1
Gene Name (Vector)
GPN-loop GTPase 1
Gene Symbol
GPN1
HGNC ID
HGNC:17030
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1125
ORF Size (bp)
1125 bp
Protein Name (eCommerce)
GPN-loop GTPase 1
RefSeq ID
NM_007266
RefSeq Synonyms
NM_007266, NM_001145049, NM_001145048, NM_001145047, BC007451,
Research Areas
Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
GPN-loop GTPase 1 (GPN1) forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. GPN1 may be involved in nuclear localization of XPA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9HCN4].
UniGene ID
Hs.18259
UniProt ID (eCommerce)
Q9HCN4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.