human GPD1 Over-expression AAV

Name
AAV-h-GPD1

Cat No
AAV-210223

Availability
4-5 weeks

This is an AAV expressing Human GPD1.

AAV-210223

AAV-h-GPD1

Ready-to-use AAV expressing Human GPD1 (glycerol-3-phosphate dehydrogenase 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GPD-C; GPDH-C; HTGTI

Description (Vector)

GPD1 encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

2819

Gene Name (Vector)

glycerol-3-phosphate dehydrogenase 1

Gene Symbol

GPD1

HGNC ID

HGNC:4455

ORF Size (aa)

1050

ORF Size (bp)

1050 bp

RefSeq ID

NM_005276

RefSeq Synonyms

NM_005276, NM_001257199, BC032234,

Species

human

UniGene ID

Hs.524418

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.