human GLRX3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-209999
Availability:
3-5 weeks
Name:
AAV-h-GLRX3
This is an AAV expressing Human GLRX3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GLRX3
- Gene Name
- glutaredoxin 3
- Gene ID
- 10539
- Gene Synonyms
- GLRX4; GRX3; GRX4; PICOT; TXNL2; TXNL3
- ORF Size
- 1008 bp
- RefSeq#
- BC005289
- Gene Description
- GLRX3 encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.
- UniGene ID
- Hs.42644
- HGNC ID
- HGNC:15987
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