human GJB3 Over-expression AAV

Name 
AAV-h-GJB3
Cat No 
AAV-209925
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GJB3.

AAV-209925
AAV-h-GJB3

Ready-to-use AAV expressing Human GJB3 (gap junction protein beta 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CX31; DFNA2; DFNA2B; EKV
Description (Vector)
GJB3 is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene ID
2707
Gene Name (Vector)
gap junction protein beta 3
Gene Symbol
GJB3
HGNC ID
HGNC:4285
ORF Size (aa)
813
ORF Size (bp)
813 bp
RefSeq ID
NM_024009
RefSeq Synonyms
NM_024009, NM_001005752, BC110640, BC012918,
Species
human
UniGene ID
Hs.522561

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.