human GCNT2 Over-expression AAV

Name 
AAV-h-GCNT2
Cat No 
AAV-209756
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GCNT2.

AAV-209756
AAV-h-GCNT2

Ready-to-use AAV expressing Human GCNT2 (glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA360O19.2; bA421M1.1; CCAT; CTRCT13; GCNT2C; GCNT5; IGNT; II; NACGT1; NAGCT1; ULG3
Description (Vector)
GCNT2 encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
2651
Gene Name (Vector)
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
Gene Symbol
GCNT2
HGNC ID
HGNC:4204
ORF Size (aa)
1209
ORF Size (bp)
1209 bp
RefSeq ID
NM_145649
RefSeq Synonyms
NM_145655, NM_145649, NM_001491, BC130524, BC074802, BC074801,
Species
human
UniGene ID
Hs.519884

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.