human FZD8 Over-expression AAV

Name 
AAV-h-FZD8
Cat No 
AAV-209470
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FZD8.

AAV-209470
AAV-h-FZD8

Ready-to-use AAV expressing Human FZD8 (frizzled class receptor 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FZ-8; hFZ8
Description (Vector)
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Gene ID
8325
Gene Name (Vector)
frizzled class receptor 8
Gene Symbol
FZD8
HGNC ID
HGNC:4046
ORF Size (aa)
2082
ORF Size (bp)
2082 bp
RefSeq ID
NM_031866
RefSeq Synonyms
NM_031866, BC111845,
Species
human
UniGene ID
Hs.302634

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.