human FZD4 Over-expression AAV

Name 
AAV-h-FZD4
Cat No 
AAV-209464
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FZD4.

AAV-209464
AAV-h-FZD4

Ready-to-use AAV expressing Human FZD4 (frizzled class receptor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD344; EVR1; FEVR; Fz-4; Fz4; FZD4S; FzE4; GPCR; hFz4
Description (Vector)
FZD4 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.
Gene ID
8322
Gene Name (Vector)
frizzled class receptor 4
Gene Symbol
FZD4
HGNC ID
HGNC:4042
ORF Size (aa)
1614
ORF Size (bp)
1614 bp
RefSeq ID
NM_012193
RefSeq Synonyms
NM_012193, BC114622, BC114527,
Species
human
UniGene ID
Hs.591968

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.