human FSCN2 Over-expression AAV

Name
AAV-h-FSCN2

Cat No
AAV-209338

Availability
4-5 weeks

This is an AAV expressing Human FSCN2.

AAV-209338

AAV-h-FSCN2

Ready-to-use AAV expressing Human FSCN2 (fascin actin-bundling protein 2, retinal). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RFSN; RP30

Description (Vector)

FSCN2 encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

25794

Gene Name (Vector)

fascin actin-bundling protein 2, retinal

Gene Symbol

FSCN2

HGNC ID

HGNC:3960

ORF Size (aa)

1479

ORF Size (bp)

1479 bp

RefSeq ID

NM_012418

RefSeq Synonyms

NM_012418, NM_001077182, BC130330, BC126295,

Species

human

UniGene ID

Hs.118555

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.