human FEV Over-expression AAV

Name 
AAV-h-FEV
Cat No 
AAV-208918
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FEV.

AAV-208918
AAV-h-FEV

Ready-to-use AAV expressing Human FEV (FEV, ETS transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HSRNAFEV; PET-1
Description (Vector)
FEV belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. FEV is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.
Gene ID
54738
Gene Name (Vector)
FEV, ETS transcription factor
Gene Symbol
FEV
HGNC ID
HGNC:18562
ORF Size (aa)
717
ORF Size (bp)
717 bp
RefSeq ID
NM_017521
RefSeq Synonyms
NM_017521, BC023511,
Species
human
UniGene ID
Hs.234759

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.