human FASTK Over-expression AAV

Name
AAV-h-FASTK

Cat No
AAV-208725

Availability
4-5 weeks

This is an AAV expressing Human FASTK.

AAV-208725

AAV-h-FASTK

Ready-to-use AAV expressing Human FASTK (Fas activated serine/threonine kinase). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FAST

Description (Vector)

FASTK is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

Gene ID

10922

Gene Name (Vector)

Fas activated serine/threonine kinase

Gene Symbol

FASTK

HGNC ID

HGNC:24676

ORF Size (aa)

1650

ORF Size (bp)

1650 bp

RefSeq ID

NM_006712

RefSeq Synonyms

NM_033015, NM_006712, NM_001258461, BC039026, BC011770, BC000377,

Species

human

UniGene ID

Hs.647094

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.