human RHEB Over-expression AAV

Name 
AAV-h-RHEB
Cat No 
AAV-208542
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RHEB.

AAV-208542
AAV-h-RHEB

Ready-to-use AAV expressing Human RHEB (Ras homolog enriched in brain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RHEB2
Description (Vector)
RHEB is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Gene ID
6009
Gene Name (Vector)
Ras homolog enriched in brain
Gene Symbol
RHEB
HGNC ID
HGNC:10011
ORF Size (aa)
555
RefSeq ID
NM_005614
RefSeq Synonyms
NM_005614, BC107705, BC066307, BC016155,
Species
human
UniGene ID
Hs.283521

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.