human RHEB shRNA silencing Adenovirus

Name 
Ad-h-RHEB-shRNA
Cat No 
shADV-208542
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RHEB.

shADV-208542
Ad-h-RHEB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RHEB (Ras homolog enriched in brain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
RHEB2
Description (Vector)
RHEB is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Gene ID
6009
Gene Name (Vector)
Ras homolog enriched in brain
Gene Symbol
RHEB
HGNC ID
HGNC:10011
ORF Size (aa)
555
RefSeq ID
NM_005614
RefSeq Synonyms
NM_005614, BC107705, BC066307, BC016155,
Species
human
UniGene ID
Hs.283521

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.