human FA2H Over-expression AAV

Name
AAV-h-FA2H

Cat No
AAV-208239

Availability
4-5 weeks

This is an AAV expressing Human FA2H.

AAV-208239

AAV-h-FA2H

Ready-to-use AAV expressing Human FA2H (fatty acid 2-hydroxylase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FAAH; FAH1; FAXDC1; SCS7; SPG35

Description (Vector)

FA2H encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.

Gene ID

79152

Gene Name (Vector)

fatty acid 2-hydroxylase

Gene Symbol

FA2H

HGNC ID

HGNC:21197

ORF Size (aa)

1119

ORF Size (bp)

1119 bp

RefSeq ID

NM_024306

RefSeq Synonyms

NM_024306, BC017049, BC010453, BC004263, BC002679,

Species

human

UniGene ID

Hs.461329

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.