human EZR Over-expression AAV

Name
AAV-h-EZR

Cat No
AAV-208213

Availability
4-5 weeks

Categories
AAV, Over-Expression

This is an AAV expressing Human EZR.

AAV-208213

AAV-h-EZR

Ready-to-use AAV expressing Human EZR (ezrin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CVIL; CVL; HEL-S-105; VIL2

Description (Vector)

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Gene ID

7430

Gene Name (Vector)

ezrin

Gene Symbol

EZR

HGNC ID

HGNC:12691

ORF Size (aa)

1761

ORF Size (bp)

1761 bp

RefSeq ID

NM_003379

RefSeq Synonyms

NM_003379, NM_001111077, BC068458, BC013903,

Species

human

UniGene ID

Hs.487027

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.