human EXOC5 Over-expression AAV

Name 
AAV-h-EXOC5
Cat No 
AAV-208177
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EXOC5.

AAV-208177
AAV-h-EXOC5

Ready-to-use AAV expressing Human EXOC5 (exocyst complex component 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
exocyst complex component 5; exocyst complex component Sec10; HSEC10; PRO1912; SEC10; SEC10L1; SEC10-like 1; SEC10P
Description (eCommerce)
EXOC5 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including EXOC5, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity [taken from NCBI Entrez Gene (Gene ID: 10640)].
Description (Vector)
EXOC5 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Gene ID
10640
Gene Name (eCommerce)
exocyst complex component 5
Gene Name (Vector)
exocyst complex component 5
Gene Symbol
EXOC5
HGNC ID
HGNC:10696
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2127
ORF Size (bp)
2127 bp
Protein Name (eCommerce)
Exocyst complex component 5
RefSeq ID
NM_006544
RefSeq Synonyms
NM_006544, BC041126,
Research Areas
Golgi Apparatus,Insulin Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
EXOC5 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including EXOC5, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity [taken from NCBI Entrez Gene (Gene ID: 10640)].
UniGene ID
Hs.715522
UniProt ID (eCommerce)
O00471

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.