human ETV1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-208142
Availability:
3-5 weeks
Name:
AAV-h-ETV1
This is an AAV expressing Human ETV1.
Request a Quote
Please enter your email address and we'll be in touch with more information:
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ETV1
- Gene Name
- ETS variant 1
- Gene ID
- 2115
- Gene Synonyms
- ER81
- ORF Size
- 1434 bp
- RefSeq#
- BC106763
- Gene Description
- ETV1 encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA(AT)-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. ETV1 is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Erwing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- UniGene ID
- Hs.22634
- HGNC ID
- HGNC:3490
Related Products
Product | Cat No. |
---|---|
AAV-m-ETV1 | AAV-258742 |
Ad-h-ETV1 | ADV-208142 |
Ad-m-ETV1 | ADV-258742 |
AAV-h-ETV1-shRNA | shAAV-208142 |
AAV-m-ETV1-shRNA | shAAV-258742 |
Ad-h-ETV1-shRNA | shADV-208142 |
Ad-m-ETV1-shRNA | shADV-258742 |
Control Products
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
Privacy Policy