human ETFA Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-208133
Availability:
3-5 weeks
Name:
AAV-h-ETFA
This is an AAV expressing Human ETFA.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ETFA
- Gene Name
- electron transfer flavoprotein alpha subunit
- Gene ID
- 2108
- Gene Synonyms
- EMA; GA2; MADD
- ORF Size
- 1002 bp
- RefSeq#
- BC095457
- Gene Description
- ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.39925
- HGNC ID
- HGNC:3481
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