human ERAP2 Over-expression AAV

Name 
AAV-h-ERAP2
Cat No 
AAV-208038
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ERAP2.

AAV-208038
AAV-h-ERAP2

Ready-to-use AAV expressing Human ERAP2 (endoplasmic reticulum aminopeptidase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
L-RAP; LRAP
Description (Vector)
Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP1 (MIM 606832) and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II (TPP2; MIM 190470) (Tanioka et al., 2003 (PubMed 12799365)).(supplied by OMIM, Mar 2008)
Gene ID
64167
Gene Name (Vector)
endoplasmic reticulum aminopeptidase 2
Gene Symbol
ERAP2
HGNC ID
HGNC:29499
ORF Size (aa)
2748
ORF Size (bp)
2748 bp
RefSeq ID
NM_022350
RefSeq Synonyms
NM_022350, NM_001329233, NM_001329229, NM_001130140, BC065240,
Species
human
UniGene ID
Hs.482910

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.