human EPOR Over-expression AAV

Name 
AAV-h-EPOR
Cat No 
AAV-208018
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EPOR.

AAV-208018
AAV-h-EPOR

Ready-to-use AAV expressing Human EPOR (erythropoietin receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EPO-R
Description (Vector)
EPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Gene ID
2057
Gene Name (Vector)
erythropoietin receptor
Gene Symbol
EPOR
HGNC ID
HGNC:3416
ORF Size (aa)
1527
ORF Size (bp)
1527 bp
RefSeq ID
NM_000121
RefSeq Synonyms
NM_000121, BC112153,
Species
human
UniGene ID
Hs.631624

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.