human EDA Over-expression AAV

Name
AAV-h-EDA

Cat No
AAV-207547

Availability
4-5 weeks

This is an AAV expressing Human EDA.

AAV-207547

AAV-h-EDA

Ready-to-use AAV expressing Human EDA (ectodysplasin A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ECTD1; ED1; ED1-A1; ED1-A2; EDA-A1; EDA-A2; EDA1; EDA2; HED; HED1; ODT1; STHAGX1; TNLG7C; XHED; XLHED

Description (Vector)

EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.

Gene ID

1896

Gene Name (Vector)

ectodysplasin A

Gene Symbol

EDA

HGNC ID

HGNC:3157

ORF Size (aa)

1161

ORF Size (bp)

1161 bp

RefSeq ID

NM_001005609

RefSeq Synonyms

NM_001399, NM_001005613, NM_001005612, NM_001005610, NM_001005609, BC144051, BC144049, BC126143,

Species

human

UniGene ID

Hs.105407

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.