human DYNC1LI1 Over-expression AAV

Name 
AAV-h-DYNC1LI1
Cat No 
AAV-207464
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DYNC1LI1.

AAV-207464
AAV-h-DYNC1LI1

Ready-to-use AAV expressing Human DYNC1LI1 (dynein cytoplasmic 1 light intermediate chain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cytoplasmic dynein 1 light intermediate chain 1; DLC-A; DNCLI1; dynein light chain A; dynein light intermediate chain 1, cytosolic; dynein, cytoplasmic, light intermediate polypeptide 1; LIC1
Description (eCommerce)
Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. It may play a role in binding dynein to membranous organelles or chromosomes and is probably involved in the microtubule-dependent transport of pericentrin. DYNC1LI1 Is required for progress through the spindle assembly checkpoint [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y6G9].
Gene ID
51143
Gene Name (eCommerce)
dynein cytoplasmic 1 light intermediate chain 1
Gene Name (Vector)
dynein cytoplasmic 1 light intermediate chain 1
Gene Symbol
DYNC1LI1
HGNC ID
HGNC:18745
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1572
ORF Size (bp)
1572 bp
Protein Name (eCommerce)
Cytoplasmic dynein 1 light intermediate chain 1
RefSeq ID
NM_016141
RefSeq Synonyms
NM_016141, NM_001329135, BC131620,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Host-Virus Interactions,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,infectious_disease
Species
human
Target Sentence
Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. It may play a role in binding dynein to membranous organelles or chromosomes and is probably involved in the microtubule-dependent transport of pericentrin. DYNC1LI1 Is required for progress through the spindle assembly checkpoint [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y6G9].
UniGene ID
Hs.529495
UniProt ID (eCommerce)
Q9Y6G9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.