mouse DYNC1LI1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Dync1li1.
shADV-257570
Ad-m-DYNC1LI1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dync1li1 (dynein cytoplasmic 1 light intermediate chain 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110053F02Rik; Dnclic1; LIC-1
Description (Vector)
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
Gene ID
235661
Gene Name (Vector)
dynein cytoplasmic 1 light intermediate chain 1
Gene Symbol
Dync1li1
ORF Size (aa)
1572
ORF Size (bp)
1572 bp
RefSeq ID
NM_146229
RefSeq Synonyms
NM_146229, BC023347,
Species
mouse
UniGene ID
Mm.128627
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.