human DSC1 Over-expression AAV

Name 
AAV-h-DSC1
Cat No 
AAV-207335
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DSC1.

AAV-207335
AAV-h-DSC1

Ready-to-use AAV expressing Human DSC1 (desmocollin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CDHF1; DG2/DG3
Description (Vector)
DSC1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.
Gene ID
1823
Gene Name (Vector)
desmocollin 1
Gene Symbol
DSC1
HGNC ID
HGNC:3035
ORF Size (aa)
2682
ORF Size (bp)
2682 bp
RefSeq ID
NM_004948
RefSeq Synonyms
NM_024421, NM_004948, BC148349,
Species
human
UniGene ID
Hs.567260

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.