human DOK7 Over-expression AAV

Name 
AAV-h-DOK7
Cat No 
AAV-207251
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DOK7.

AAV-207251
AAV-h-DOK7

Ready-to-use AAV expressing Human DOK7 (docking protein 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C4orf25; CMS10; CMS1B
Description (Vector)
DOK7 is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
Gene ID
285489
Gene Name (Vector)
docking protein 7
Gene Symbol
DOK7
HGNC ID
HGNC:26594
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_173660
RefSeq Synonyms
NM_173660, NM_001301071, NM_001256896, NM_001164673, BC141852, BC131544,
Species
human
UniGene ID
Hs.701584

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.