human DNASE2 Over-expression AAV
This is an AAV expressing Human DNASE2.
AAV-207192
AAV-h-DNASE2
Ready-to-use AAV expressing Human DNASE2 (deoxyribonuclease 2, lysosomal). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DNASE2A; DNL; DNL2
Description (Vector)
DNASE2 encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.
Gene ID
1777
Gene Name (Vector)
deoxyribonuclease 2, lysosomal
Gene Symbol
DNASE2
HGNC ID
HGNC:2960
ORF Size (aa)
1083
ORF Size (bp)
1083 bp
RefSeq ID
NM_001375
RefSeq Synonyms
NM_001375, BC065209, BC010419,
Species
human
UniGene ID
Hs.118243
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.