human DKK1 Over-expression AAV

Name 
AAV-h-DKK1
Cat No 
AAV-207023
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DKK1.

AAV-207023
AAV-h-DKK1

Ready-to-use AAV expressing Human DKK1 (dickkopf WNT signaling pathway inhibitor 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DKK-1; SK
Description (Vector)
DKK1 encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Gene ID
22943
Gene Name (Vector)
dickkopf WNT signaling pathway inhibitor 1
Gene Symbol
DKK1
HGNC ID
HGNC:2891
ORF Size (aa)
801
ORF Size (bp)
801 bp
RefSeq ID
NM_012242
RefSeq Synonyms
NM_012242, BC001539,
Species
human
UniGene ID
Hs.40499

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.