human DIABLO Over-expression AAV

Name 
AAV-h-DIABLO
Cat No 
AAV-206982
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DIABLO.

AAV-206982
AAV-h-DIABLO

Ready-to-use AAV expressing Human DIABLO (diablo IAP-binding mitochondrial protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DFNA64; SMAC
Description (Vector)
DIABLO encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein.
Gene ID
56616
Gene Name (Vector)
diablo IAP-binding mitochondrial protein
Gene Symbol
DIABLO
HGNC ID
HGNC:21528
ORF Size (aa)
720
ORF Size (bp)
720 bp
RefSeq ID
NM_019887
RefSeq Synonyms
NM_138930, NM_138929, NM_019887, NM_001278342, NM_001278304, NM_001278303, NM_001278302, BC095468, BC011909,
Species
human
UniGene ID
Hs.169611

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.