human DCTD Over-expression AAV

Name 
AAV-h-DCTD
Cat No 
AAV-206671
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DCTD.

AAV-206671
AAV-h-DCTD

Ready-to-use AAV expressing Human DCTD (dCMP deaminase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
DCTD catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
1635
Gene Name (Vector)
dCMP deaminase
Gene Symbol
DCTD
HGNC ID
HGNC:2710
ORF Size (aa)
537
ORF Size (bp)
537 bp
RefSeq ID
NM_001921
RefSeq Synonyms
NM_001921, NM_001012732, BC088357, BC001286,
Species
human
UniGene ID
Hs.183850

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.