human D2HGDH Over-expression AAV
This is an AAV expressing Human D2HGDH.
AAV-206556
AAV-h-D2HGDH
Ready-to-use AAV expressing Human D2HGDH (D-2-hydroxyglutarate dehydrogenase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D2HGD
Description (Vector)
D2HGDH encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
Gene ID
728294
Gene Name (Vector)
D-2-hydroxyglutarate dehydrogenase
Gene Symbol
D2HGDH
HGNC ID
HGNC:28358
ORF Size (aa)
1566
ORF Size (bp)
1566 bp
RefSeq ID
NM_152783
RefSeq Synonyms
NM_152783, NM_001287249, BC071598, BC036604, BC031817,
Species
human
UniGene ID
Hs.535639
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.