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human CTSD Over-expression AAV

Name 
AAV-h-CTSD
Cat No 
AAV-206267
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CTSD.

AAV-206267
AAV-h-CTSD

Ready-to-use AAV expressing Human CTSD (cathepsin D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CLN10; CPSD; HEL-S-130P
Description (Vector)
CTSD encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.
Gene ID
1509
Gene Name (Vector)
cathepsin D
Gene Symbol
CTSD
HGNC ID
HGNC:2529
ORF Size (aa)
1239
ORF Size (bp)
1239 bp
RefSeq ID
NM_001909
RefSeq Synonyms
NM_001909, BC016320,
Species
human
UniGene ID
Hs.654447

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.