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human CTAG2 Over-expression AAV

Name 
AAV-h-CTAG2
Cat No 
AAV-206214
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CTAG2.

AAV-206214
AAV-h-CTAG2

Ready-to-use AAV expressing Human CTAG2 (cancer/testis antigen 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAMEL; CT2; CT6.2; CT6.2a; CT6.2b; ESO2; LAGE-1; LAGE2B
Description (Vector)
CTAG2 encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID 10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants.
Gene ID
30848
Gene Name (Vector)
cancer/testis antigen 2
Gene Symbol
CTAG2
HGNC ID
HGNC:2492
ORF Size (aa)
543
ORF Size (bp)
543 bp
RefSeq ID
NM_020994
RefSeq Synonyms
NM_172377, NM_020994, BC128045, BC113998, BC002833,
Species
human
UniGene ID
Hs.87225

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.