human CRTC1 Over-expression AAV

Name
AAV-h-CRTC1

Cat No
AAV-206038

Availability
4-5 weeks

This is an AAV expressing Human CRTC1.

AAV-206038

AAV-h-CRTC1

Ready-to-use AAV expressing Human CRTC1 (CREB regulated transcription coactivator 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CREB-regulated transcription coactivator 1; Mam-2; MAML2; Mastermind-like protein 2; MECT1; mucoepidermoid carcinoma translocated protein 1; TORC1; TORC-1; Transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; Transducer of regulated cAMP response element-binding protein 1; WAMTP1

Description (eCommerce)

TORC1 (transducer of regulated CREB activity 1) is part of a family of CREB (cAMP response element-binding protein) coactivators that also includes TORC2 and TORC3. These proteins function to activate CREB-dependent transcription in response to cAMP and calcium signaling pathways. The TORC family of proteins has been shown to regulate transcription of PGC-1 alpha, a regulator of mitochondrial genes.

Gene ID

23373

Gene Name (eCommerce)

CREB regulated transcription coactivator 1

Gene Name (Vector)

CREB regulated transcription coactivator 1

Gene Symbol

CRTC1

HGNC ID

HGNC:16062

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1905

ORF Size (bp)

1905 bp

Protein Name (eCommerce)

CREB-regulated transcription coactivator 1

RefSeq ID

NM_015321

RefSeq Synonyms

NM_015321, NM_001098482, BC028050,

Research Areas

BDNF Signaling,Cancer,Host-Virus Interactions,Neurobiology,Transcription Factor/Regulator,Tumor Suppressors/Oncoproteins

Research Areas (Faceted)

cancer,cell_biology,infectious_disease,neurobiology,signal_transduction,transcription_translation

Species

human

Target Sentence

TORC1 (transducer of regulated CREB activity 1) is part of a family of CREB (cAMP response element-binding protein) coactivators that also includes TORC2 and TORC3. These proteins function to activate CREB-dependent transcription in response to cAMP and calcium signaling pathways. The TORC family of proteins has been shown to regulate transcription of PGC-1 alpha, a regulator of mitochondrial genes.

UniGene ID

Hs.371096

UniProt ID (eCommerce)

Q6UUV9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.