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human CROT Over-expression AAV

Name 
AAV-h-CROT
Cat No 
AAV-206033
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CROT.

AAV-206033
AAV-h-CROT

Ready-to-use AAV expressing Human CROT (carnitine O-octanoyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COT
Description (Vector)
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
Gene ID
54677
Gene Name (Vector)
carnitine O-octanoyltransferase
Gene Symbol
CROT
HGNC ID
HGNC:2366
ORF Size (aa)
1839
ORF Size (bp)
1839 bp
RefSeq ID
NM_021151
RefSeq Synonyms
NM_021151, NM_001243745, NM_001143935, BC051874, BC039004,
Species
human
UniGene ID
Hs.125039

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.