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human COX4I2 Over-expression AAV

Name 
AAV-h-COX4I2
Cat No 
AAV-205829
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human COX4I2.

AAV-205829
AAV-h-COX4I2

Ready-to-use AAV expressing Human COX4I2 (cytochrome c oxidase subunit 4I2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COX4; COX4-2; COX4B; COX4L2; COXIV-2; dJ857M17.2
Description (Vector)
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation.
Gene ID
84701
Gene Name (Vector)
cytochrome c oxidase subunit 4I2
Gene Symbol
COX4I2
HGNC ID
HGNC:16232
ORF Size (aa)
516
ORF Size (bp)
516 bp
RefSeq ID
NM_032609
RefSeq Synonyms
NM_032609, BC057779,
Species
human
UniGene ID
Hs.277101

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.