human CFL2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-205053
Availability:
3-5 weeks
Name:
AAV-h-CFL2
This is an AAV expressing Human CFL2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CFL2
- Gene Name
- cofilin 2
- Gene ID
- 1073
- Gene Synonyms
- NEM7
- ORF Size
- 501 bp
- RefSeq#
- BC011444
- Gene Description
- CFL2 encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
- UniGene ID
- Hs.180141
- HGNC ID
- HGNC:1875
Related Products
Product | Cat No. |
---|---|
AAV-m-CFL2 | AAV-255340 |
Ad-h-CFL2 | ADV-205053 |
Ad-m-CFL2 | ADV-255340 |
AAV-h-CFL2-shRNA | shAAV-205053 |
AAV-m-CFL2-shRNA | shAAV-255340 |
Ad-h-CFL2-shRNA | shADV-205053 |
Ad-m-CFL2-shRNA | shADV-255340 |
Control Products
Vector Biolabs
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Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
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Fax: +1 215-525-1112
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